Answer:
The active functional group of a drug is that one that has the most prominent quality of adherence to the corresponding group on the target site and this selective binding of the group gave the property of targeted therapy and action. The pharmacophore modelling is done to ensure the design success of a drug but real life circumstances are mostly unpredictable. By this specific targeted action a drug acquires the property of differentiating between healthy and infected cells. Infected cells always have something different in their functional group expression as compare the the healthy cells. This helps the drug to differentiate between them.
The typical dosage of statin drugs for the treatment of high cholesterol is 10 mg.Assuming a total blood volume of 5.0 L and the density of blood in healthy individuals is approximately 1.05 g/mL, report the concentration of drug in units of ppm.
Answer:
1.904 ppm
Explanation:
Concentration of drug in units of ppm = mass of solute ÷ (mass of solution ) × 1000000
mass of blood = density of blood × volume = 1.05 g / ml × 5000 ml = 5250 g
mass of solution = mass of blood + mass of solute ( statin) = 5250 + 0.01 g = 5250.01 g
Concentration of drug in units of ppm = (0.01 g / 5250.01 g) × 1000000 = 1.904 ppm
Nerve fibers from all regions of the retina converge on the ___ and exit the eye by way of the optic nerve.
Answer: Optic Disc
Explanation:Optic Disc is a portion of the eye,it can be seen as black spot on the eye,it doesn't contain rods. Optic disc is the point of exit for optic nerve.
The optic disc is also known as the optic nerve Head,it is made up of connective and elastic tissue, it is the passage to the nerve fibre bundles and retinal blood vessels it also maintain intra-ocular pressure against a gradient between the intra-ocular and extra-ocular spaces.
Answer:Nerve fibers from all regions of the retina converge on the optic disc and exit the eye by way of the optic nerve.
Explanation: The eye is part of the sense organs which is used for visual purposes. It is made up if different parts that aid to achieve its visual functions, they include:
Lens, retina, optic nerve, cornea and many among others.
The images that are reflected through the len on the retina is converted into a set of electrical signals, and these signals are transmitted to the brain through complex neural pathways that connect the eye via the optic nerve to the visual cortex and other areas of the brain.
The optic nerve is made up of ganglion cell axon while the optic disc represents the beginning of the optic nerve and is the point where the axons of retinal ganglion cells come together. I hope this helps, thanks.
According to the __________ strategy, fertility is a pattern of behavior tied closely to the institutional and organizational structure of society. Select one: a. family planning b. societalist c. coercion d. developmentalist
Ovulation typically produces just one egg per cycle. Why does ejaculate contain more than just one sperm?
Explanation:
The female reproductive system produces one egg cell every month but males can ejaculate about 50 million sperm cells to fertilise one egg cell as:
1. The sperms released from the males are killed by the acidic nature of the cervix due to the acidic secretion of the female reproductive structure.
2. The sperms get trapped in the structure of the cervix which reduces the chances of reaching the egg cell.
3. only a few sperms reach the egg cell out of which only one sperm cell fuses with the egg cell and the rest are degraded by the system.
Thus, male ejaculate a large number of cells.
Which organization is responsible for the continuation of defining, explaining, classifying, and researching summary statements about health problems related to nursing?
Answer:
The North American Nursing Diagnosis Association-International (NANDA-I)
Explanation:
NANDA International (formerly the North American Nursing Diagnosis Association) is a professional organization of nurses interested in standardized nursing terminology, that was officially founded in 1982 and develops, researches, disseminates and refines the nomenclature, criteria, and taxonomy of nursing diagnoses.
Which opiate causes euphoria, relaxation, drowsiness, and detachment from reality and has possible effects on the pregnancy, including preeclampsia, intrauterine growth restriction, and premature rupture of membranes?
Answer:
Heroin (opiate) causes euphoria, relaxation, drowsiness, and detachment from reality and has possible effects on the pregnancy, including preeclampsia, intrauterine growth restriction, and premature rupture of membranes.
Explanation:
OPIATES are a group of CNS drugs which include :
1) Heroin.
2) Meperidine.
3) Methadone.
4) Codeine.
5) Buprenorphine.
They act on number of receptors in order to produce their effects especially analgesia.
Heroin can cause following signs and symptoms :
1) Analgesia ( relief from pain ) : by increasing pain tolerance and decreasing pain perception.
2) Euphoria and relaxation : Heroin changes back to morphine in the brain , acts on opiod receptors and produce euphoria and relaxation.
3) Detachment from reality : As the prolonged use of heroin can change the functional level of the brain, it causes detachment from reality.
Effects on pregnancy ( Preeclampsia , intrauterine growth restriction and premature rupture of membranes ) : These effects occur with heroin because it crosses the placental membrane and causes the relaxation ( inhibition of uterine contractions ) and also causes respiratory depression in the newborn. Hence opiates are strongly prohibited in pregnancy.